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We demonstrated the improvements of an optical biosensor system using a long range surface plasma resonance technique. As preliminary simulation results, we present the prism-based biosensor system with a broader operating range to improve the sensitivity for a wider the measurable reflective index range and a narrower absorbing peak. This proposed optical biosensor system could be used to implement a compact immunoassay device.
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Dianwen Zhang, XiaoCong Yuan, Swee Chuan Tjin, B. K. Ng, C. Y. Fu, R. Irawan, "Surface plasma resonance biosensor based on prism geometry," Proc. SPIE 5270, Environmental Monitoring and Remediation III, (4 March 2004); https://doi.org/10.1117/12.524493