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13 July 2004 A scanned focused ultrasound device for hyperthermia: numerical simulation and prototype implementation
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We are developing a scanned focused ultrasound system for hyperthermia treatment of breast cancer. Focused ultrasound has significant potential as a therapy delivery device because it can focus sufficient heating energy below the skin surface with minimal damage to intervening tissue. However, as a practical therapy system, the focal zone is generally quite small and requires either electronic (in the case of a phased array system) or mechanical steering (for a fixed bowl transducer) to cover a therapeutically useful area. We have devised a simple automated steering system consisting of a focused bowl transducer supported by three vertically movable rods which are connected to computer controlled linear actuators. This scheme is particularly attractive for breast cancer hyperthermia where the support rods can be fed through the base of a liquid coupling tank to treat tumors within the breast while coupled to our noninvasive microwave thermal imaging system. A MATLAB routine has been developed for controlling the rod motion such that the beam focal point scans a horizontal spiral and the subsequent heating zone is cylindrical. In coordination with this effort, a 3D finite element thermal model has been developed to evaluate the temperature distributions from the scanned focused heating. In this way, scanning protocols can be optimized to deliver the most uniform temperature rise to the desired location.
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Paul M. Meaney, Timothy Raynolds, Shireen D. Geimer, Lincoln Potwin, and Keith D. Paulsen "A scanned focused ultrasound device for hyperthermia: numerical simulation and prototype implementation", Proc. SPIE 5312, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XIV, (13 July 2004);

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