1 July 2004 Reducing speckle noise in retinal OCT images by aligning multiple B-scans
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The application of Optical Coherence Tomography (OCT) within ophthalmology is today relative widespread, the reason being that it is a major help in revealing details of structural damage and retinal patho-physiology that otherwise can be difficult to detect. Yet, there is still space for improvement and the OCT systems continuously improve both their speed and resolution. Besides the possibility of upgrading the hardware there is however also a possibility for "bootstrapping" the present generation of commercial devices by adequate post-processing of the acquired signals. We present evidence that with an existing commercial system it is possible to improve the signal-to-noise ratio of the recorded images by fusing multiple scans of the same retinal region. In order to achieve this improvement it is necessary to align a number of noisy signals. We have explored a number of different techniques for achieving this goal. The improvement is sufficient to reveal details that are impossible or difficult to observe from the individual OCT recordings.
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Thomas Martini Jorgensen, Thomas Martini Jorgensen, Bjarne Ersboll, Bjarne Ersboll, Birgit Sander, Birgit Sander, Michael Larsen, Michael Larsen, "Reducing speckle noise in retinal OCT images by aligning multiple B-scans", Proc. SPIE 5316, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine VIII, (1 July 2004); doi: 10.1117/12.529158; https://doi.org/10.1117/12.529158


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