1 July 2004 Creating the invisible man
Author Affiliations +
Proceedings Volume 5319, Laser Interaction with Tissue and Cells XV; (2004); doi: 10.1117/12.537256
Event: Biomedical Optics 2004, 2004, San Jose, CA, United States
Abstract
Our recent research has shown that skin becomes temporarily transparent when a hyper-osmotic agent such as glycerol is introduced into the tissue. Local dehydration and index matching reduce light scattering which increases the penetration depth of collimated light. We have shown that when glycerol is applied to in vivo hamster skin, the resulting transparency is sufficient to allow visualization of blood vessels, and there is a temporary reduction in local blood flow. The reduced blood flow combined with greater light delivery significantly reduces the laser fluence rate [W/cm2] required to coagulate dermal blood vessels.
© (2004) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
A. J. Welch, Chris Humphrey, Gracie Vargas, Oliver F. Stumpp, Chris G. Rylander, "Creating the invisible man", Proc. SPIE 5319, Laser Interaction with Tissue and Cells XV, (1 July 2004); doi: 10.1117/12.537256; https://doi.org/10.1117/12.537256
PROCEEDINGS
6 PAGES


SHARE
KEYWORDS
Skin

Blood vessels

In vivo imaging

Blood circulation

Tissues

Refractive index

Tissue optics

Back to Top