Translator Disclaimer
18 June 2004 Measurement of refractive index variation of physiological analytes using differential-phase OCT
Author Affiliations +
Abstract
We report results of a study using differential phase optical coherence tomography (DP-OCT) for measurement of variation of refractive index (n) vs. analyte concentration (C) in translucent solutions and turbid tissue phantoms. Variation of refractive index with analyte concentration (dn/dC) in aqueous solutions of glucose, calcium chloride, magnesium chloride, sodium chloride, potassium chloride, potassium bicarbonate, urea, bovine serum albumin, and bovine globulin was measured. Obtained results demonstrated: (1) dn/dC for glucose is significantly greater than that of other analytes in the physiological range; and (2) high sensitivity of DP-OCT method for measurement of analyte concentration.
© (2004) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Kirill V. Larin, Taner Akkin, Thomas E. Milner, Digand P. Dave, Massoud Motamedi, and Rinat O. Esenaliev "Measurement of refractive index variation of physiological analytes using differential-phase OCT", Proc. SPIE 5325, Optical Diagnostics and Sensing IV, (18 June 2004); https://doi.org/10.1117/12.532004
PROCEEDINGS
4 PAGES


SHARE
Advertisement
Advertisement
Back to Top