14 June 2004 Novel near-infrared nanoparticlulate biomarker: preparation and stability studies
Author Affiliations +
Degradation of Indocyanine green (ICG) in aqueous media, limits its application in early tumor diagnosis and therapy. Thus, the objective of this study is to develop biodegradable nanoparticles entrapping ICG and to establish its effectiveness in providing overall stability to ICG. Nanoparticles entrapping ICG were engineered and characterized. The degradation kinetics of ICG in the nanoparticles was investigated in aqueous media. The degradation of ICG in aqueous nanoparticle suspension followed first-order kinetics. Nanoparticles enhanced aqueous, photo and thermal-stability of ICG.
© (2004) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Vishal Saxena, Vishal Saxena, Mostafa Sadoqi, Mostafa Sadoqi, Sunil Kumar, Sunil Kumar, Jun Shao, Jun Shao, } "Novel near-infrared nanoparticlulate biomarker: preparation and stability studies", Proc. SPIE 5329, Genetically Engineered and Optical Probes for Biomedical Applications II, (14 June 2004); doi: 10.1117/12.534317; https://doi.org/10.1117/12.534317

Back to Top