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23 December 2003 Culture-based biochip for environmental monitoring
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Proceedings Volume 5345, Microfluidics, BioMEMS, and Medical Microsystems II; (2003)
Event: Micromachining and Microfabrication, 2004, San Jose, California, United States
In this paper, we describe the development of a culture-based biochip for detecting mycobacteria in environmental samples. The biochips use the paraffinophilic nature of mycobacteria to rapidly detect and differentiate them from non-target micro-organisms. New methods of depositing and patterning paraffin were developed to fabricate prototype biochips. Biochips were experimentally tested to demonstrate rapid detection of mycobacteria in environmental samples collected from a municipal sewage treatment plant. Our successful demonstration of the culture-based biochip technology presents an alternative approach for developing new technology to track microorganisms in complex environmental samples.
© (2003) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Gaoshan Jing, Daniel B. Oerther, and Ian Papautsky "Culture-based biochip for environmental monitoring", Proc. SPIE 5345, Microfluidics, BioMEMS, and Medical Microsystems II, (23 December 2003);

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