23 December 2003 Separation of blood in microchannel bends
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Proceedings Volume 5345, Microfluidics, BioMEMS, and Medical Microsystems II; (2003) https://doi.org/10.1117/12.522780
Event: Micromachining and Microfabrication, 2004, San Jose, California, United States
Abstract
Biological applications of micro assay devices require integrated on-chip microfluidics for separation of plasma or serum from blood. This is achieved by a new blood separation technique based on a microchannel bend structure developed within the collaborative Micro-Tele-BioChip (μTBC) project co-funded by the German Ministry For Education and Research (BMBF). Different prototype polymer chips have been manufactured with an UV-LIGA process and hot embossing technology. The separation efficiency of these chips has been determined by experimental measurements using human whole blood. Results show different separation efficiencies for cells and plasma depending on microchannel geometry and blood sample characteristics and suggest an alternative blood separation method as compared to existing micro separation technologies.
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Christoph Blattert, Christoph Blattert, Reinhold Jurischka, Reinhold Jurischka, Andreas Schoth, Andreas Schoth, Paul Kerth, Paul Kerth, Wolfgang Menz, Wolfgang Menz, } "Separation of blood in microchannel bends", Proc. SPIE 5345, Microfluidics, BioMEMS, and Medical Microsystems II, (23 December 2003); doi: 10.1117/12.522780; https://doi.org/10.1117/12.522780
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