Finite-element method for intermodality nonrigid breast registration using external skin markers

Ioana L. Coman; Andrzej Krol; James A. Mandel; Karl G. Baum; Min Luo; Edward D. Lipson; David H. Feiglin

doi:10.1117/12.536144

12 May 2004 Finite-element method for intermodality nonrigid breast registration using external skin markers

Ioana L. Coman, Andrzej Krol, James A. Mandel, Karl G. Baum, Min Luo, Edward D. Lipson, David H. Feiglin

Proceedings Volume 5370, Medical Imaging 2004: Image Processing; (2004) https://doi.org/10.1117/12.536144
Event: Medical Imaging 2004, 2004, San Diego, California, United States

Abstract

We are developing a method using nonrigid co-registration of PET and MR breast images as a way to improve diagnostic specificity in difficult-to-interpret mammograms, and ultimately to avoid biopsy. A deformable breast model based on a finite-element method (FEM) has been employed. The FEM “loads” are taken as the observed intermodality displacements of several fiducial skin markers placed on the breast and visible in PET and MRI. The analogy between orthogonal components of the displacement field and the temperature differences in a steady-state heat transfer (SSHT) in solids has been adopted. The model allows estimation, throughout the breast, of the intermodality displacement field. To test our model, an elastic breast phantom with simulated internal "lesions" and external markers was imaged with PET and MRI. We have estimated fiducial- and target-registration errors vs. number and location of fiducials, and have shown that the SSHT approach using external fiducial markers is accurate to within ~5 mm.

Citation Download Citation

Ioana L. Coman, Andrzej Krol, James A. Mandel, Karl G. Baum, Min Luo, Edward D. Lipson, and David H. Feiglin "Finite-element method for intermodality nonrigid breast registration using external skin markers", Proc. SPIE 5370, Medical Imaging 2004: Image Processing, (12 May 2004); https://doi.org/10.1117/12.536144

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