Computer-aided detection of lung cancer on chest radiographs: effect of machine CAD true positive/false negative detections on radiologists' confidence level

Matthew T. Freedman M.D.; Teresa Osicka; Shih-Chung Benedict Lo; Fleming Lure; Xin-Wei Xu; Jesse Lin; Hui Zhao; Ron Zhang

doi:10.1117/12.536157

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4 May 2004 Computer-aided detection of lung cancer on chest radiographs: effect of machine CAD true positive/false negative detections on radiologists' confidence level

Matthew T. Freedman M.D., Teresa Osicka, Shih-Chung Benedict Lo, Fleming Lure, Xin-Wei Xu, Jesse Lin, Hui Zhao, Ron Zhang

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Proceedings Volume 5372, Medical Imaging 2004: Image Perception, Observer Performance, and Technology Assessment; (2004) https://doi.org/10.1117/12.536157
Event: Medical Imaging 2004, 2004, San Diego, California, United States

Abstract

This paper evaluates the effect of Computer-Aided Detection prompts on the confidence and detection of cancer on chest radiographs. Expected findings included an increase in confidence rating and a decrease in variance in confidence when radiologists interacted with a computer prompt that confirmed their initial decision or induced them to switch from an incorrect to a correct decision. Their confidence rating decreased and the variance of confidence rating increased when the computer failed to confirm a correct or incorrect decision. A population of cases was identified that changed among reading modalities. This unstable group of cases differed between the Independent and Sequential without CAD modalities in cancer detection by radiologists and cancer detection by machine. CAD prompts induced the radiologists to make two types of changes in cases: changes on the sequential modality with CAD that restored an initial diagnosis made in the Independent read and new changes that were not present in the Independent or Sequential reads without CAD. This has implications for double reading of cases. The effects of intra-observer variability and inter-observer variability are suggested as potential causes for differences in statistical significance of the Independent and Sequential Design approaches to ROC studies.

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Matthew T. Freedman M.D., Teresa Osicka, Shih-Chung Benedict Lo, Fleming Lure, Xin-Wei Xu, Jesse Lin, Hui Zhao, and Ron Zhang "Computer-aided detection of lung cancer on chest radiographs: effect of machine CAD true positive/false negative detections on radiologists' confidence level", Proc. SPIE 5372, Medical Imaging 2004: Image Perception, Observer Performance, and Technology Assessment, (4 May 2004); https://doi.org/10.1117/12.536157

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