15 October 2004 Water-soluble 1,4-bis(4-aminostyryl)benzene derivatives for biological two-photon applications
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Abstract
1,4-Bis(4-aminostyryl)benzene derivatives have been shown to exhibit large two-photon cross-sections at ca. 730-745 nm and are typically highly fluorescent in organic solvents. For biological imaging applications, we have been interested in identifying water-soluble dyes with high two-photon cross-sections and fluorescence quantum yields. Four new bis(aminostyryl)benzene chromophores have been synthesized; these chromophores are functionalized with phosphate, sulfonate, and sulfate hydrophilic groups. In some cases, this substitution pattern renders the chromophores water-soluble and, for the sulfonate and sulfate cases, moderate fluorescence quantum yields are retained in water.
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Lisa M. Dollinger, Timothy C. Parker, Judith M. Lavin, Stephanie J.K. Pond, Mariacristina Rumi, Stephen Barlow, Joseph W. Perry, Seth R. Marder, "Water-soluble 1,4-bis(4-aminostyryl)benzene derivatives for biological two-photon applications", Proc. SPIE 5516, Nonlinear Optical Transmission and Multiphoton Processes in Organics II, (15 October 2004); doi: 10.1117/12.561852; https://doi.org/10.1117/12.561852
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