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22 October 2004 Technical feasibility evaluation of fluorescence signal detection by compact photonic explorer for better health
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Abstract
The lowest detectable fluorescence signal level from biomedical specimens have been determined using a spectrometer, cooled CCD detector, and PIN photodiode with 365 nm UV LED light excitation. The data indicates the PIN photodiodes have adequate sensitivity for detection of tissue fluorescence with a sufficient signal-to-noise ratio. This data is being used to design a "pill-sized" Compact Photonics Explorer (CPE) for in vivo cancer optical diagnostics.
© (2004) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Gang Zhang, LeMing Wang, Q. Z. Wang, J.-C. Luo, Fanan Zeng, Manuel Zevallos, Yury Budansky, Scott Alfano, Alvin Katz, and R. R. Alfano "Technical feasibility evaluation of fluorescence signal detection by compact photonic explorer for better health", Proc. SPIE 5524, Novel Optical Systems Design and Optimization VII, (22 October 2004); https://doi.org/10.1117/12.559963
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