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26 October 2004 Microphase-contrast x-ray computed tomography for basic biomedical study at SPring-8
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Abstract
Micro-phase-contrast X-ray computed tomography with an X-ray interferometer (micro-phase-contrast CT) is in operation to obtain high spatial resolution images of less than 0.01 mm at the undulator beam-line 20XU of SPring-8, Japan, and we applied micro-phase-contrast CT to observe the organs of rats and hamsters. The excised kidney and spleen fixed by formalin were imaged. The fine inner-structures such as vessels, glomeruli of kidney and white and red pulps of spleen were visualized clearly about 0.01-mm spatial resolutions without using contrast agent or staining procedure. The results were very similar to those by optical microscopic images with 20-fold magnification. These results suggest that the micro-phase tomography might be a useful tool for various biomedical researches.
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Jin Wu R.N., Tohoru Takeda M.D., Thet-Thet Lwin M.D., Ichiro Koyama, Atsushi Momose, Akiko Fujii, Yoshitaka Hamaishi, Taichi Kuroe, Tetsuya Yuasa, Yoshio Suzuki, and Takao Akatsuka "Microphase-contrast x-ray computed tomography for basic biomedical study at SPring-8", Proc. SPIE 5535, Developments in X-Ray Tomography IV, (26 October 2004); https://doi.org/10.1117/12.559390
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