26 October 2004 Ultrafast micro-CT for in vivo small animal imaging and industrial applications
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Abstract
A new, ultra-fast microCT instrument with scanning+reconstruction cycle under 50 seconds for full 3D-volume has been created. The scanner based on the scanning geometry with static object and rotation of source-camera pair(s), which allows using it for industrial applications as well as for low-dose in-vivo imaging of small laboratory animals where rotation of the object is not acceptable. Acquisition part contains two pairs of x-ray sources and cameras for data collection from complementary directions simultaneously. Reconstruction engine (cone-beam reconstruction by modified Feldkamp algotithm) includes 1, 2 or 4 dual Intel-Xeon computers working in parallel under control of the host PC through local network. The instrument specifications are following: voxel size is 48 or 96 um for corresponding 1024x1024x1024 or 512x512x512 reconstruction array; scanning time with parallel reconstruction is 50 seconds for 96um resolution. X-ray sources peak energy can be adjusted in the range of 20-65kV. Typical scanning dose is 0.4Gy. The scanner itself is a compact desktop instrument, which contains all x-ray parts and necessary shielding for safe operations in the normal laboratory environments.
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Alexander Sasov, "Ultrafast micro-CT for in vivo small animal imaging and industrial applications", Proc. SPIE 5535, Developments in X-Ray Tomography IV, (26 October 2004); doi: 10.1117/12.559011; https://doi.org/10.1117/12.559011
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KEYWORDS
X-rays

Scanners

Cameras

In vivo imaging

X-ray sources

Ultrafast phenomena

Preclinical imaging

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