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9 December 2004Manipulation of optical properties of human skin by light scattering nanoparticles of titanium dioxide
An acute problem to protect human skin against harmful UV solar rays emerged in recent years because of increased occasions of skin cancer. The aim of this research is to evaluate, how optical properties of the horny layer of human skin can be changed by imbedding the titanium dioxide (TiO2) fine particles in order to achieve the maximal attenuation of the UV solar radiation. In-depth distribution in the skin of TiO2 particles typically achieved with the sunscreens is determined experimentally by the tape-stripping technique. Computer code implementing the Monte Carlo method is used to simulate photon migration within 20-mm thick horny layer partially filled with nano-sized TiO2 spheres. Dependencies of absorbed by and reflected from, as well as transmitted through the horny layer UV radiation of two wavelengths (310 and 400 nm) on the concentration of TiO2 particles are obtained and analyzed.
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Alexey P. Popov, Alexander V. Priezzhev, Jurgen Lademann, Risto Myllyla, "Manipulation of optical properties of human skin by light scattering nanoparticles of titanium dioxide," Proc. SPIE 5578, Photonics North 2004: Photonic Applications in Astronomy, Biomedicine, Imaging, Materials Processing, and Education, (9 December 2004); https://doi.org/10.1117/12.567423