Optical characteristics of biological molecules in the terahertz gap

Tatiana Globus; Ramakrishnan Parthasarathy; Tatyana Khromova; Dwight L. Woolard; Nathan Swami; Andrew J. Gatesman; Jerry Waldman

doi:10.1117/12.580838

14 December 2004 Optical characteristics of biological molecules in the terahertz gap

Tatiana Globus, Ramakrishnan Parthasarathy, Tatyana Khromova, Dwight L. Woolard, Nathan Swami, Andrew J. Gatesman, Jerry Waldman

Author Affiliations +

Proceedings Volume 5584, Chemical and Biological Standoff Detection II; (2004) https://doi.org/10.1117/12.580838
Event: Optics East, 2004, Philadelphia, Pennsylvania, United States

Abstract

Terahertz Spectroscopy has been recently introduced as a promising technique for the collection of signature data in transmission spectra of biological materials including warfare agent simulants. To characterize material rather than sample, it is always desirable to obtain the material's optical properties as functions of frequency. In this work, we present results from parallel measurements of reflection and transmission spectra of biological molecules to enable detailed and direct calculation of refractive index and absorption coefficient spectra in the terahertz gap. DNA samples from herring and salmon as well as samples of Ovalbumin and Bacillus Subtillus spores have been characterized. The technique for simulation is described. Reflection spectra reveal resonance features similar to those demonstrated earlier for transmission, thereby affirming molecular vibrational modes in biological materials. The dispersion of refractive index and absorption coefficient is demonstrated within the Terahertz gap of 10 cm^-1 to 25 cm^-1.

Citation Download Citation

Tatiana Globus, Ramakrishnan Parthasarathy, Tatyana Khromova, Dwight L. Woolard, Nathan Swami, Andrew J. Gatesman, and Jerry Waldman "Optical characteristics of biological molecules in the terahertz gap", Proc. SPIE 5584, Chemical and Biological Standoff Detection II, (14 December 2004); https://doi.org/10.1117/12.580838

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