14 December 2004 A performance-optimized optical fiber bio-probe for cancerous tissue characterization
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Proceedings Volume 5589, Fiber Optic Sensor Technology and Applications III; (2004); doi: 10.1117/12.571489
Event: Optics East, 2004, Philadelphia, Pennsylvania, United States
Abstract
Auto fluorescence of tissue depends not only on the concentration of fluoro-phores present in tissues but also on the configuration of optical fiber sensor. In this paper, feasibility of using laser induced fluorescence spectroscopy as a diagnostic tool for distinguishing malignant animal tissue from its normal counterpart under various design configurations is explored. Three different design configurations are tested for the performance optimization. The optimized Y-shaped optical reflection fiber probe gives the best laser induced fluorescence signal comparing to other probes. This instrument incorporated a continuous wave (CW) Nd:YAG laser operating at 532 nm.
© (2004) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Chan Kyu Kim, Sunil K. Khijwania, Jagdish P. Singh, "A performance-optimized optical fiber bio-probe for cancerous tissue characterization", Proc. SPIE 5589, Fiber Optic Sensor Technology and Applications III, (14 December 2004); doi: 10.1117/12.571489; https://doi.org/10.1117/12.571489
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KEYWORDS
Tissues

Tissue optics

Ocean optics

Laser induced fluorescence

Optical fibers

Luminescence

Cancer

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