The hybridization specificity of DNA allows the design of sets of oligomers which, when mixed together, self-assemble into complex nanoscale structures. Such structures can be induced to undergo configuration changes by incorporating motor domains consisting of regions of single-stranded DNA to which complementary "fuel" strands can hybridize. The principles of operation of these devices and prospects for making free-running DNA-based molecular motors are described. Potential applications for these devices, including the construction of materials whose mechanical properties can be altered in the response to the presence of specific oligomers, will be described.
Bernard Yurke, Bernard Yurke,
"Using DNA to assemble and power the nanoworld", Proc. SPIE 5592, Nanofabrication: Technologies, Devices, and Applications, (19 January 2005); doi: 10.1117/12.580241; https://doi.org/10.1117/12.580241