10 September 2004 Experimental study using ER-YAG laser in discs: changes in glycosaminoglycan content and synthesis in discs
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Proceedings Volume 5610, Laser Florence 2003: A Window on the Laser Medicine World; (2004) https://doi.org/10.1117/12.584329
Event: Laser Florence 2003: A Window on the Laser Medicine World, 2003, Florence, Italy
Abstract
Changes in discs after Er-Yag laser irradiation are scarcely reported. We made an experimental study using white rabbits and Er-Yag laser. Under general anesthesia, Er-Yag laser was irradiated into lumbar discs. Three or 8 weeks after irradiation, rabbits were sacrificed, and these discs were extracted. The quantitative analysis of the glycosaminoglycan content in the annulus fibrosus, and the incorporation of 35S-sulfate in chondroitin 4 sulfate were measured. The results showed, the increased incorporation of 35S-sulfate in chondroitin 4 sulfate and chondroitin 6 sulfates in groups of laser irradiation may indicate Er-Yag laser irradiation in nucleus pulposus, accelerated glycosaminoglycan production, in the annulus fibrosus. But no difference of unsaturated isomers of chondroitin 4 sulfate, and chondroitin 6 sulfate, and no difference of saturated isomer of keratan sulfate indicate, the influence of Er-Yag laser irradiation was not so high, as to bring the quantitative changes of matrix of annulus fibrosus in term of 8 weeks.
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Kazuyuki Maehara, Kazuyuki Maehara, Sadaaki Nakai, Sadaaki Nakai, Kumi Naga, Kumi Naga, Seiji Nishimoto, Seiji Nishimoto, } "Experimental study using ER-YAG laser in discs: changes in glycosaminoglycan content and synthesis in discs", Proc. SPIE 5610, Laser Florence 2003: A Window on the Laser Medicine World, (10 September 2004); doi: 10.1117/12.584329; https://doi.org/10.1117/12.584329
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