Clinical research on erythrocyte deformability with different doses of He-Ne exposure in patient with ischemia disease

Yanping Zhao; Song-hao Liu; Jinbo Sun; Gangyue Luo; Rong Hua; Qianqin Liu

doi:10.1117/12.577184

18 January 2005 Clinical research on erythrocyte deformability with different doses of He-Ne exposure in patient with ischemia disease

Yanping Zhao, Song-hao Liu, Jinbo Sun, Gangyue Luo, Rong Hua, Qianqin Liu

Author Affiliations +

Proceedings Volume 5630, Optics in Health Care and Biomedical Optics: Diagnostics and Treatment II; (2005) https://doi.org/10.1117/12.577184
Event: Photonics Asia, 2004, Beijing, China

Abstract

The aim of this study was to test human erythrocyte deformability with the exposure of erythrocyte from apoplexy patient and other ischemia diseases, contracted with normal donors' blood sample, and the doses-effect of Low-power He_Ne laser in vitro were discussed. Fresh blood sample from adult health donors and patients with different diseases such as apoplexy, diabetes, heart block etc in emergency department were collected and divided into different groups in which there were no less than 6 persons. Fresh human blood samples were irradiated with a He-Ne laser (Lamba=632.8nm), power output around 4.5MW, 9MW, 15mW, and 18mW, et al., exposure time from 7.5min, 15min, and 30min, operating in continuous wave. Measurements of human erythrocyte deformability were taken. Erythrocyte deformability appearance shown some different in the health contracted group and the other ischemia disease group. Some notice difference also shown among some disease group with nonirradiation and the same disease group with laser irradiation. The dose-effects of He-Ne laser therapy was discussed on the further research on the erythrocyte deformability of blood sample from patients with apoplexy disease treated with He-Ne laser at different doses, and a certain optimal doses which could take a beneficial effect in clinic were speculated on. This study revealed that the He-Ne laser have some different effects on erythrocyte deformability in vitro, which were related with the disease condition, red cell state, and outpower-doses, et al closely.

Citation Download Citation

Yanping Zhao, Song-hao Liu, Jinbo Sun, Gangyue Luo, Rong Hua, and Qianqin Liu "Clinical research on erythrocyte deformability with different doses of He-Ne exposure in patient with ischemia disease", Proc. SPIE 5630, Optics in Health Care and Biomedical Optics: Diagnostics and Treatment II, (18 January 2005); https://doi.org/10.1117/12.577184

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