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18 January 2005 Effects of flowing scatters on measured backscattering signal
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Optical Coherence Tomography (OCT) is a noninvasive cross-sectional imaging modality capable of measuring tissue morphology and function high spatial resolution. The amplitude of the intero-metric heterodyne signal provides a profile of sample reflectivity related to its microstructure and its phase may enable bi-directional blood flowing imaging, termed Color Doppler OCT (CDOCT). In order to evaluate and improve the imaging properties as well as find the appropriate image-processing algorithms, several theoretical models of OCT of biological tissue have been proposed. Most of these models are based on the consideration of both the single scattering and multiple scattering processes of the light within the tissues. However, all these models omitted the effects of moving scatterers on measured backscattering signal. We show that inclusion of this effect is more realized and is of great importance in the calculation and interpretation of the heterodyne signal, evaluation of the system performance as well as calculating the maximum imaging depth of the OCT scanners. The analytical results and a sample result is given.
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Wanrong Gao and Maohai Hu "Effects of flowing scatters on measured backscattering signal", Proc. SPIE 5630, Optics in Health Care and Biomedical Optics: Diagnostics and Treatment II, (18 January 2005);

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