Noninvasive method to determine the optical property of biological tissue by ultrasound modulation and diffuse reflection light

Hui Li; Cuncheng Weng; Lanqing Xu; Shusen Xie

doi:10.1117/12.576860

18 January 2005 Noninvasive method to determine the optical property of biological tissue by ultrasound modulation and diffuse reflection light

Hui Li, Cuncheng Weng, Lanqing Xu, Shusen Xie

Author Affiliations +

Proceedings Volume 5630, Optics in Health Care and Biomedical Optics: Diagnostics and Treatment II; (2005) https://doi.org/10.1117/12.576860
Event: Photonics Asia, 2004, Beijing, China

Abstract

A non-invasive method to determine the optical property of biological tissue by the combination with ultrasound modulation and diffuse reflection light is firstly presented. A focused ultrasound beam through tissue has the modulated diffuse light located within the focal spot and so that the diffuse fluence distribution is easily detected from out of tissue. Based on the diffuse reflectance fitted formula concluded from Monte Carlo simulation by authors, the optical property including absorption coefficient, scattering coefficient, average scattering cosine, and even the refractive index can be rebuild. In addition, this new method is very significant to measure a light dose in vivo in laser medicine and surgery.

Citation Download Citation

Hui Li, Cuncheng Weng, Lanqing Xu, and Shusen Xie "Noninvasive method to determine the optical property of biological tissue by ultrasound modulation and diffuse reflection light", Proc. SPIE 5630, Optics in Health Care and Biomedical Optics: Diagnostics and Treatment II, (18 January 2005); https://doi.org/10.1117/12.576860

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