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18 January 2005 Physiological meaning of cerebral oxygen saturation for piglet with hypoxia-ischemia
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The physiological meaning of cerebral oxygen saturation absolute values and the oxygen metabolism of piglet with hypoxia-ischemia (HIE) were researched. The subjects were two piglets. During the total experiment of hypoxia then recovery, the regional cerebral tissue oxygen (rScO2), pulse oxygen saturation (SpO2) were detected non-invasively and the jugular oxygen saturation (SjO2), arterial oxygen saturation (SaO2) were given invasively. The results show that because SjO2 was equal to or larger than rScO2 and SaO2 > ScO2, rScO2 cannot be determined by the weighted sum of SjO2 and SaO2 which had been presented in some papers. According to above-mentioned analysis, the ecchymoma and pathological changes of the vessels due to HIE may be another contribution of rScO2. SjO2 was correlated with SaO2 (R=0.996 and 0.962 for two piglets) and the values of (SaO2-SjO2) are close to constants (29.3±8% and 30.3±8%).It means that because the subjects were under anesthesia, the oxygen consumption of cerebral tissue kept constants.
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Haishu Ding, Lan Huang, Chungchien Jen, Betau Hwang, Zhiguang Lee, Yichao Teng, and Meizhi Zheng "Physiological meaning of cerebral oxygen saturation for piglet with hypoxia-ischemia", Proc. SPIE 5630, Optics in Health Care and Biomedical Optics: Diagnostics and Treatment II, (18 January 2005);

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