18 January 2005 UPT-based biosensor and its application
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An up-converting phosphor technology-based biosensor (UPT-based biosensor) has been developed for immunoassay using Up-converting phosphor (UCP) as the biological marker. The UPT system has realized quantitative detection and has good ability to meet the need of some emergencies. High sensitivity (nanogram/ml), good linear response characteristics and an excellent correlation (R2greater than or equal to 0.95) have been verified by quantitative detection results. The sensitivity of the UPT-based biosensor is better than that of the indirect hemagglutination test in the practical application. All the results are comparable with that obtained by Western Blot detection.
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Yongkai Zhao, Yongkai Zhao, Lei Zhou, Lei Zhou, Huijie Huang, Huijie Huang, Ruifu Yang, Ruifu Yang, Lihua Huang, Lihua Huang, Bingqiang Ren, Bingqiang Ren, Jian Lu, Jian Lu, Xiangzhao Wang, Xiangzhao Wang, "UPT-based biosensor and its application", Proc. SPIE 5630, Optics in Health Care and Biomedical Optics: Diagnostics and Treatment II, (18 January 2005); doi: 10.1117/12.577006; https://doi.org/10.1117/12.577006

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