A series of inorganic-organic photochromic ultra-thin films were fabricated by self-assembly. The photochromic properties as well as structure of the prepared ultra-thin films were discussed. It is found that the photochromic properties of the ultra-thin films were closely related to the building blocks of the films. Both the organic and the inorganic components of the self-assembled films can evidently effect the structure and photochromism properties. The optimized combination of the inorganic and organic building blocks is thus provided.