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16 February 2005 PDMS valves in DNA computers
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DNA computing is an interdisciplinary field accessing the possibility for the use of biomolecules, such as DNA, RNA and proteins, as a computational or control tool. Traditionally, DNA computers were thought to compete with electronic computers to solve, for example, NP-complete problems. However recently, there has been a focus shift to biomedical applications. One form of DNA computing is performed in microfluidics. A network of microreactors decides the computational aspects and DNA is the tool for selection procedures. To control complex microflow systems like this, a series of pneumatic valves are used to control the flow direction, i.e. the information direction, and to contain DNA functionalised beads in the microreactors.
© (2005) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Danny van Noort and Byoung-Tak Zhang "PDMS valves in DNA computers", Proc. SPIE 5651, Biomedical Applications of Micro- and Nanoengineering II, (16 February 2005);

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