The National Aeronautics and Space Administration (NASA), Aeronautics Research Mission Directorate, is developing Intelligent Mission Management (IMM) technology for Uninhabited Aerial Vehicles (UAV’s) under the Vehicle Systems Program’s Autonomous Robust Avionics Project. The objective of the project is to develop air vehicle and associated ground element technology to enhance mission success by increasing mission return and reducing mission risk. Unanticipated science targets, uncertain conditions and changing mission requirements can all influence a flight plan and may require human intervention during the flight; however, time delays and communications bandwidth limit opportunities for operator intervention. To meet these challenges, we will develop UAV-specific technologies enabling goal-directed autonomy, i.e. the ability to redirect the flight in response to current conditions and the current goals of the flight. Our approach divides goal-directed autonomy into two components, an on-board Intelligent Agent Architecture (IAA) and a ground based Collaborative Decision Environment (CDE). These technologies cut across all aspects of a UAV system, including the payload, inner- and outer-loop onboard control, and the operator’s ground station.