25 April 2005 Clinical feasibility of various optical instruments for quantitative evaluation of pulsed-dye laser treatment of port wine stain skin
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Abstract
For quantitative prediction and evaluation of pulsed dye laser therapy of port wine stain (PWS) skin, the CIE L*a*b* color difference, ΔE*, has been utilized to characterize numerically the color differences between normal untreated and treated PWS skin. Three optical instruments (Minolta chromameter CR-200, a cross-polarized diffuse reflectance imaging system, and visual reflectance spectrometers) are compared to investigate their clinical feasibility for quantitative color assessment. Compared to the chromameter as a standard measurement instrument, other instruments also provide valuable measurements of skin color for the relative quantification of PWS treatment outcome. The fiber-optic visual reflectance spectrometer is preferable for continuous measurement of a small area of skin. The cross-polarized imaging system is useful as a simple non-contact measurement technique to provide spatially resolved color difference images.
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Chang-Seok Kim, Chang-Seok Kim, Byungjo Jung, Byungjo Jung, Bernard Choi, Bernard Choi, Wim Verkruysse, Wim Verkruysse, Rong Zhang, Rong Zhang, John Stuart Nelson, John Stuart Nelson, "Clinical feasibility of various optical instruments for quantitative evaluation of pulsed-dye laser treatment of port wine stain skin", Proc. SPIE 5686, Photonic Therapeutics and Diagnostics, (25 April 2005); doi: 10.1117/12.589706; https://doi.org/10.1117/12.589706
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