28 April 2005 Hemodynamic variations measured with near-infrared spectroscopy in human forearm muscles in response to venous occlusion: an electrical model
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Abstract
We present data collected with near-infrared spectroscopy on the human forearm (brachioradialis muscle) to characterize the hemodynamic response to venous occlusion in muscle. Venous occlusion was achieved in the upper arm by inflating a pneumatic cuff to a pressure of 60 mmHg. We performed absolute measurements of concentration and oxygen saturation of hemoglobin on six healthy adult human subjects. On all six subjects, we consistently found that during a 40-s venous occlusion the hemoglobin concentration increases (by 5.6±2.3 μM), while the oxygen saturation of hemoglobin decreases (by 2.1±0.7%). This accumulation and desaturation of blood in the forearm in response to the upper arm occlusion can be described with an electrical model in which the charge stored by a capacitor represents the local blood volume, and the electrical current represents blood flow.
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Vo Van Toi, Matthew L. Hoimes, Shalini Nadgir, Sergio Fantini, "Hemodynamic variations measured with near-infrared spectroscopy in human forearm muscles in response to venous occlusion: an electrical model", Proc. SPIE 5693, Optical Tomography and Spectroscopy of Tissue VI, (28 April 2005); doi: 10.1117/12.589302; https://doi.org/10.1117/12.589302
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