15 April 2005 Bulk tissue optical parameters of porcine skin dermis at 8 wavelengths from 325 to 1550nm
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Abstract
Investigation of tissue optics requires accurate values of the bulk optical parameters: the scattering coefficient μs, absorption coefficient μa, anisotropy factor g and the real refractive index nr. We employed a coherent reflectance curve method to determine the refractive index of fresh porcine skin dermis at 8 wavelengths between 325 and 1557nm. The surface profiles of fresh dermis samples were measured with a non-contact method of confocal imaging and the roughness parameters were extracted. To determine tissue optical parameters, a single integrating sphere was used to measure the diffused reflectance and transmittance with slab samples of fresh porcine skin dermis. Collimated transmittance was measured with the samples in situ using a spatial filtering setup. Based on these results, a Monte Carlo code capable of handling surface roughness of the tissue sample has been developed and used to inversely determine the bulk values of μs, μa and g at the 8 wavelengths which are significantly different from the reported values.
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Xiaoyan Ma, Xiaoyan Ma, Huafeng Ding, Huafeng Ding, Jun Q. Lu, Jun Q. Lu, Kenneth M. Jacobs, Kenneth M. Jacobs, Yousu Sun, Yousu Sun, Xin-Hua Hu, Xin-Hua Hu, "Bulk tissue optical parameters of porcine skin dermis at 8 wavelengths from 325 to 1550nm", Proc. SPIE 5695, Optical Interactions with Tissue and Cells XVI, (15 April 2005); doi: 10.1117/12.589647; https://doi.org/10.1117/12.589647
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