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25 April 2005 Opto-acoustic signal detection with a coherent confocal microscope setup
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A new approach to the detection of opto-acoustic signals with the use of single-scattered optical fields in low scattering media is presented with the ultimate goal of performing opto-acoustic confocal microscopy in human skin. The method is based on the generation of heterodyne optical signals using opto-acoustic generated signals as a source of particle displacement. A focused, pulsed laser is used to generate an opto-acoustic signal and the particle displacement detection is performed with a coherent confocal microscope. The goal is to improve the depth of imaging obtained by confocal microscopy while maintaining its resolution. The use of optical coherent detection of teh Doppler shifts generated by teh ultrasound filed positioned at the optical focus gives us information about the amplitude and phase of the the scattered optical field. The results of interferometric measurements at different depths into scattering phantoms are presented.
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Alex Nieva, Matthew Bouchard, and Charles A. DiMarzio "Opto-acoustic signal detection with a coherent confocal microscope setup", Proc. SPIE 5697, Photons Plus Ultrasound: Imaging and Sensing 2005: The Sixth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics, (25 April 2005);

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