Advanced multifocus confocal laser scanning microscope for single molecule studies

Thomas Dertinger; Felix Koberling; Ales Benda; Rainer Erdmann; Martin Hof; Joerg Enderlein

doi:10.1117/12.611147

29 March 2005 Advanced multifocus confocal laser scanning microscope for single molecule studies

Thomas Dertinger, Felix Koberling, Ales Benda, Rainer Erdmann, Martin Hof, Joerg Enderlein

Proceedings Volume 5699, Imaging, Manipulation, and Analysis of Biomolecules and Cells: Fundamentals and Applications III; (2005) https://doi.org/10.1117/12.611147
Event: SPIE BiOS, 2005, San Jose, CA, United States

Abstract

A new multi-focus multi-confocal set-up for performing fluorescence spectroscopy of single molecules in solution is presented. The ultimate goal of the set-up is to track individual molecules during diffusion in solution, when all standard methods of trapping such as optical tweezers or dielectrophoretic traps fail. We present here a detailed description of the experimental setup and show first experimental results.

Citation Download Citation

Thomas Dertinger, Felix Koberling, Ales Benda, Rainer Erdmann, Martin Hof, and Joerg Enderlein "Advanced multifocus confocal laser scanning microscope for single molecule studies", Proc. SPIE 5699, Imaging, Manipulation, and Analysis of Biomolecules and Cells: Fundamentals and Applications III, (29 March 2005); https://doi.org/10.1117/12.611147

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