28 April 2005 Enhancing the photoluminescence of peptide-coated nanocrystals
Author Affiliations +
Colloidal NCs consist of an inorganic particle and an organic coating that determines their solubility, functionality, and influences their photophysics. In order for these NCs to be biocompatible, they must be water-soluble, nontoxic to the cell, and offer conjugation chemistries for attaching recognition molecules to their surfaces. In addition they should efficiently target to biomolecules of interest, be chemically stable, and preserve their high photostability. The requirements for their application in single-molecule biological studies are even more stringent: fluorescent NCs should be monodisperse, have relatively small size (to limit steric hindrance), reduced blinking, large saturation intensity, and high quantum yield (QY).
© (2005) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
James M. Tsay, James M. Tsay, Soeren Doose, Soeren Doose, Fabien Pinaud, Fabien Pinaud, Shimon Weiss, Shimon Weiss, } "Enhancing the photoluminescence of peptide-coated nanocrystals", Proc. SPIE 5705, Nanobiophotonics and Biomedical Applications II, (28 April 2005); doi: 10.1117/12.589458; https://doi.org/10.1117/12.589458

Back to Top