28 April 2005 Interfacing peptides identified using phage-display screening with quantum dots for the design of nanoprobes
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Abstract
The interface of targeting molecules that can recognize and identify specific biomolecules with highly luminescent semiconductor nanocrystals or quantum dots can lead to a novel and powerful new class of probes for studying biomolecules in real-time or for imaging and detecting diseases. We describe the rationale design of optical nanoprobes by using fluorescent semiconductor quantum dots with targeting molecules (TMs)-identified using phage display screening. Quantum dots are nanometer-sized particles with unique and tunable optical properties. They offer numerous optical advantages over traditional organic fluorophores in biological analysis and detection (e.g., photostability, continuous absorption profile).
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Sawitri Mardyani, Sawitri Mardyani, Anupam Singhal, Anupam Singhal, Wen Jiang, Wen Jiang, Warren C. W. Chan, Warren C. W. Chan, } "Interfacing peptides identified using phage-display screening with quantum dots for the design of nanoprobes", Proc. SPIE 5705, Nanobiophotonics and Biomedical Applications II, (28 April 2005); doi: 10.1117/12.601609; https://doi.org/10.1117/12.601609
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