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28 April 2005 Surfactant-assisted synthesis of water-soluble and biocompatible semiconductor quantum dot-micelles
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We report a simple and rapid method to synthesize water-soluble and biocompatible fluorescent quantum dot (QD)-micelles by encapsulation of monodisperse, hydrophobic QDs inside surfactant/lipid micelles. Analysis of UV-vis spectra, transmission electron microscopy, and photo luminescence spectra indicate that the water-soluble semiconductor QD-micelles are monodisperse and retain the optical properties of the original hydrophobic QDs. The QD-micelles were shown to be biocompatible and exhibited little or no aggregation when taken up by cultured rat hippocampal neurons.
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Hongyou Fan, Erik W. Leve, Chessa Scullin, David Tallant, Michael C. Wilson, and C. Jeffrey Brinker "Surfactant-assisted synthesis of water-soluble and biocompatible semiconductor quantum dot-micelles", Proc. SPIE 5705, Nanobiophotonics and Biomedical Applications II, (28 April 2005);

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