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15 April 2005 Data mining and visualization of average images in a digital hand atlas
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We have collected a digital hand atlas containing digitized left hand radiographs of normally developed children grouped accordingly by age, sex, and race. A set of features stored in a database reflecting patient's stage of skeletal development has been calculated by automatic image processing procedures. This paper addresses a new concept, "average" image in the digital hand atlas. The "average" reference image in the digital atlas is selected for each of the groups of normal developed children with the best representative skeletal maturity based on bony features. A data mining procedure was designed and applied to find the average image through average feature vector matching. It also provides a temporary solution for the missing feature problem through polynomial regression. As more cases are added to the digital hand atlas, it can grow to provide clinicians accurate reference images to aid the bone age assessment process.
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Aifeng Zhang, Arkadiusz Gertych, Brent J. Liu, and H. K. Huang "Data mining and visualization of average images in a digital hand atlas", Proc. SPIE 5748, Medical Imaging 2005: PACS and Imaging Informatics, (15 April 2005);

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