6 May 2005 Bi-layer polypyrrole artificial muscle valves for drug delivery systems
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A miniature controllable drug delivery device in which drug release is achieved by actuating polymeric valves is introduced. The valves made in flap configuration are bilayer structures which were fabricated as a thin gold film and an electrochemically deposited polypyrrole (PPy) layer. A drug simulate was stored in a reservoir and the drug release process was accomplished by bending the bilayer flaps with a small electrical potential bias in solution. The detailed fabrication procedures of this controllable drug delivery device are presented.
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Han-Kuan Anthony Tsai, Han Xu, Jim Zoval, Marc Madou, "Bi-layer polypyrrole artificial muscle valves for drug delivery systems", Proc. SPIE 5759, Smart Structures and Materials 2005: Electroactive Polymer Actuators and Devices (EAPAD), (6 May 2005); doi: 10.1117/12.600407; https://doi.org/10.1117/12.600407

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