9 June 2005 Potentials of skin diagnostic with digital photometric patterning of backscattered linearly polarized light
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Abstract
Potentials of two modalities of skin diagnostic with focused and expanded linearly polarized probe light are studied. For the focused beam (wavelength 650 nm) the photometric patterns of light backscattered from skin and collagenous tissue phantoms were recorded using digital camera. It is shown that equiintensity contours are well fitted with ellipses that appeared to follow the orientation of collagen fibers. In the peripheral zone from the entry point of the probe beam the ratio of the ellipses semi-axes is correlated with the ratio ofreduced scattering coefficients obtained from intensity profiles. In the vicinity of the entry point it depends on the mutual orientation of polarization vector and collagen fibers. For the expanded probe beam the digital mapping of the residual polarization degree of backscattered linearly polarized light allowed visualization of the hidden structure of earlier fibrosis of the mouse skin arisen from X-ray treatment. The structure of the skin fibrosis was enhanced using Fourier transform filtering of polarization degree pattern. The pattern scanning with Pearson correlation coefficient was developed to determine the orientation and characteristic size of hidden structure. Both modalities may be potentially used for diagnostic ofskin abnormalities, such as fibrosis.
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Alexander P. Sviridov, Alexander P. Sviridov, Victor Chernomordik, Victor Chernomordik, Moinuddin Hassan, Moinuddin Hassan, Amir Gandjbakhche, Amir Gandjbakhche, } "Potentials of skin diagnostic with digital photometric patterning of backscattered linearly polarized light", Proc. SPIE 5772, Saratov Fall Meeting 2004: Coherent Optics of Ordered and Random Media V, (9 June 2005); doi: 10.1117/12.636860; https://doi.org/10.1117/12.636860
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