8 December 2004 Porous-silicon-based oligonucleotide chips
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Proceedings Volume 5774, Fifth International Conference on Thin Film Physics and Applications; (2004) https://doi.org/10.1117/12.607477
Event: Fifth International Conference on Thin Film Physics and Applications, 2004, Shanghai, China
Abstract
A novel oligonucleotide chip with porous silicon / oxidized porous silicon (PS/OPS) as its substrate has been developed. The attachment rate and detection sensitivity were improved obviously due to enormous surface area of PS/OPS compared to the existing conventional techniques. No dependence of storage condition on the detection sensitivity is found (signals variation is within SD). Stability of the oligonucleotide chips is good.
© (2004) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Li Shao, Li Shao, Shaoqiang Chen, Shaoqiang Chen, Jian Zhang, Jian Zhang, Jianzhong Zhu, Jianzhong Zhu, Ziqiang Zhu, Ziqiang Zhu, Bin Zhu, Bin Zhu, } "Porous-silicon-based oligonucleotide chips", Proc. SPIE 5774, Fifth International Conference on Thin Film Physics and Applications, (8 December 2004); doi: 10.1117/12.607477; https://doi.org/10.1117/12.607477
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