A bio-molecular inspired electronic architecture: bio-based device concepts for enhanced sensing

Dwight L. Woolard; Ying Luo; Boris L. Gelmont; Tatiana Globus; James O. Jensen

doi:10.1117/12.601029

18 May 2005 A bio-molecular inspired electronic architecture: bio-based device concepts for enhanced sensing (Invited Paper)

Dwight L. Woolard, Ying Luo, Boris L. Gelmont, Tatiana Globus, James O. Jensen

Author Affiliations +

Proceedings Volume 5790, Terahertz for Military and Security Applications III; (2005) https://doi.org/10.1117/12.601029
Event: Defense and Security, 2005, Orlando, Florida, United States

Abstract

A biological(bio)-molecular inspired electronic architecture is presented that offers the potential for defining nanoscale sensor platforms with enhanced capabilities for sensing terahertz (THz) frequency bio-signatures. This architecture makes strategic use of integrated biological elements to enable communication and high-level function within densely-packed nanoelectronic systems. In particular, this architecture introduces a new paradigm for establishing hybrid Electro-THz-Optical (ETO) communication channels where the THz-frequency spectral characteristics that are uniquely associated with the embedded bio-molecules are utilized directly. Since the functionality of this architecture is built upon the spectral characteristics of bio-molecules, this immediately allows for defining new methods for enhanced sensing of THz bio-signatures. First, this integrated sensor concept greatly facilitates the collection of THz bio-signatures associated with embedded bio-molecules via interactions with the time-dependent signals propagating through the nanoelectronic circuit. Second, it leads to a new Multi-State Spectral Sensing (MS3) approach where bio-signature information can be collected from multiple metastable state conformations. This paper will also introduce a new class of prototype devices that utilize THz-sensitive bio-molecules to achieve molecular-level sensing and functionality. Here, new simulation results are presented for a class of bio-molecular components that exhibit the prescribed type of ETO characteristics required for realizing integrated sensor platforms. Most noteworthy, this research derives THz spectral bio-signatures for organic molecules that are amenable to photo-induced metastable-state conformations and establishes an initial scientific foundation and design blueprint for an enhanced THz bio-signature sensing capability.

Citation Download Citation

Dwight L. Woolard, Ying Luo, Boris L. Gelmont, Tatiana Globus, and James O. Jensen "A bio-molecular inspired electronic architecture: bio-based device concepts for enhanced sensing (Invited Paper)", Proc. SPIE 5790, Terahertz for Military and Security Applications III, (18 May 2005); https://doi.org/10.1117/12.601029

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