12 May 2005 Specific biological agent taggants
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Abstract
The preliminary data presented here suggests that direct coating of biological agent with DNA capture elements and organic semiconductor (DALM) with chelated rare earths such as scandium, europium or neodymium can be used to track the agent, even when the biological components have been subsequently destroyed. The use of these three taggant components in conjunction with each other affords the opportunity to determine the presence of the biological agent by several methods---laser induced plasma spectroscopy, thermochemiluminescence, mass spectroscopy, polymerase chain reaction (PCR; if the primers are left on the DCEs or the agent's own DNA is used as the source of the amplicon). The specific DCE-labeling or PCR allows for confirmation of physical measurement results as specific to the agent.
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Johnathan L. Kiel, Johnathan L. Kiel, Eric A. Holwitt, Eric A. Holwitt, Jill E. Parker, Jill E. Parker, Jeeva Vivekananda, Jeeva Vivekananda, Veronica Franz, Veronica Franz, Mark A. Sloan, Mark A. Sloan, Andrzej W. Miziolek, Andrzej W. Miziolek, Frank C. DeLucia, Frank C. DeLucia, Chase A. Munson, Chase A. Munson, Yvette D. Mattley, Yvette D. Mattley, } "Specific biological agent taggants", Proc. SPIE 5795, Chemical and Biological Sensing VI, (12 May 2005); doi: 10.1117/12.597640; https://doi.org/10.1117/12.597640
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