Investigation of the influence of laser irradiation on the relative concentration of oxyhemoglobin in the blood

Mustafo M. Asimov; Alexander I. Gisbrecht; Serge A. Mamilov; Yuriy S. Plaksiy

doi:10.1117/12.618994

22 April 2005 Investigation of the influence of laser irradiation on the relative concentration of oxyhemoglobin in the blood

Mustafo M. Asimov, Alexander I. Gisbrecht, Serge A. Mamilov, Yuriy S. Plaksiy

Author Affiliations +

Proceedings Volume 5830, 13th International School on Quantum Electronics: Laser Physics and Applications; (2005) https://doi.org/10.1117/12.618994
Event: 13th International School on Quantum Electronics: Laser Physics and Applications, 2004, Bourgas, Bulgaria

Abstract

One of the mechanisms of influence of laser radiation on the biological tissue is photodissociation of oxyhemoglobin with releasing of molecular oxygen, thus decreasing the degree of blood oxygen saturation. The experimental study of oxygen saturation of arterial blood under laser action is based on the registration of small variations of the saturation value on the background of the natural saturation oscillations. While the determination of the value of oxygen saturation allows to observe respiratory processes, the value of venous saturation allows to determine the dynamics and efficiency of the oxygen absorption in tissues, as well as the condition of venous vessels. The tissue and vein oxygen saturation have not been studied sufficiently so far. The simlutaneous control of arterial and tissue saturation values will give opportunity to study the oxygen supply processes. The aims of this work are experimental study of laser induced photodissociation of oxyhemoglobin and determination of the dependence between the saturation value and the laser parameters. This will allow to develop new methods of control, as well as to realized a feedback during laser therapy.

Citation Download Citation

Mustafo M. Asimov, Alexander I. Gisbrecht, Serge A. Mamilov, and Yuriy S. Plaksiy "Investigation of the influence of laser irradiation on the relative concentration of oxyhemoglobin in the blood", Proc. SPIE 5830, 13th International School on Quantum Electronics: Laser Physics and Applications, (22 April 2005); https://doi.org/10.1117/12.618994

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