New approach to carbon monoxide poisoning treatment by laser-induced photodissociation of carboxyhemoglobin of cutaneous blood vessels

Mustafo M. Asimov; Rustam M. Asimov; Alexander Gisbrecht

doi:10.1117/12.619001

22 April 2005 New approach to carbon monoxide poisoning treatment by laser-induced photodissociation of carboxyhemoglobin of cutaneous blood vessels

Mustafo M. Asimov, Rustam M. Asimov, Alexander Gisbrecht

Author Affiliations +

Proceedings Volume 5830, 13th International School on Quantum Electronics: Laser Physics and Applications; (2005) https://doi.org/10.1117/12.619001
Event: 13th International School on Quantum Electronics: Laser Physics and Applications, 2004, Bourgas, Bulgaria

Abstract

A new approach to carbon monoxide poisoning treatment based on laser-induced photodissociation of the carboxyhemoglobin is proposed. Using the simple model of laser tissue interaction the action spectra of laser radiation on carboxyhemoglobin of cutaneous blood vessels has been calculated. The results of the calculatoins indicate that there is a relatively narrow spectral range in the visible region where one could effectively irradiate carboxyhemoglobin through the tissue not in a deep distances. In the case of deeper penetration, the action spectra of laser radiation shifts toward the longer wavelength region. Despite the similarity of the carboxyhemoglobin and oxyhemoglobin action spectra, the significant difference in quantum yields of photodissociation makes possible to develop an effective method of carbon monoxide poisoning treatment.

Citation Download Citation

Mustafo M. Asimov, Rustam M. Asimov, and Alexander Gisbrecht "New approach to carbon monoxide poisoning treatment by laser-induced photodissociation of carboxyhemoglobin of cutaneous blood vessels", Proc. SPIE 5830, 13th International School on Quantum Electronics: Laser Physics and Applications, (22 April 2005); https://doi.org/10.1117/12.619001

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