26 October 2005 Quantifiability and image quality in noncontact fluorescence tomography
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Non-contact detection schemes for optical or fluorescence tomography offer several advantages compared to classic approaches, most importantly the ability to obtain images with a CCD in the absence of a matching fluid or fiber optics. This allows the acquisition of high density datasets, as well as simplified experimental procedures. Herein we create a unified framework for contact and non-contact detection procedures and present experimental results that show the ability of the non-contact method to quantify the concentration of fluorochromes hidden in turbid media as well as the improvement in image quality between conventional and non-contact detection.
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Ralf B. Schulz, Ralf B. Schulz, Joerg Peter, Joerg Peter, Wolfhard Semmler, Wolfhard Semmler, Cosimo D'Andrea, Cosimo D'Andrea, Gianluca Valentini, Gianluca Valentini, Rinaldo Cubeddu, Rinaldo Cubeddu, } "Quantifiability and image quality in noncontact fluorescence tomography", Proc. SPIE 5859, Photon Migration and Diffuse-Light Imaging II, 58590Z (26 October 2005); doi: 10.1117/12.632855; https://doi.org/10.1117/12.632855

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