8 October 2005 Crosstalk in the measurement of focal brain activation by near-infrared topography
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Abstract
Crosstalk between oxy- and deoxy-haemoglobin observed in near-infrared topography is investigated. The light propagation in an adult head model is predicted by Monte Carlo simulation to obtain the change in intensity detected with source-detector pairs on the scalp caused by a focal absorption change in the brain. The topographic images of changes in oxy- and deoxy-haemoglobin are obtained from the changes in intensity detected with source-detector pairs on the scalp. The crosstalk depends on the relative position of the focal absorption change to source-detector pairs. The crosstalk is minimised when the focal absorption change is located below a measurement point that is the midpoint between a source and a detector. Appropriate selection of wavelength pair is effective to reduce the crosstalk in the topographic image.
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N. Okui, E. Okada, "Crosstalk in the measurement of focal brain activation by near-infrared topography", Proc. SPIE 5859, Photon Migration and Diffuse-Light Imaging II, 58591A (8 October 2005); doi: 10.1117/12.632876; https://doi.org/10.1117/12.632876
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KEYWORDS
Absorption

Tissue optics

Monte Carlo methods

Skull

Brain activation

Geometrical optics

Head

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