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7 October 2005 In vivo retinal optical coherence tomography at 1030 nm with enhanced penetration into the choroid
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Abstract
In vivo retinal imaging with ~ 8 μm axial resolution at 1030 nm is demonstrated for the first time, enabling enhanced penetration into the choroid. A new high power, broad bandwidth light source based on amplified spontaneous emission (NP Photonics, λc = 1030 nm, Δλ= 50 nm, Pout = 25 mW) has been interfaced to a time domain ophthalmic OCT system. In vivo retinal OCT tomograms performed at 800 nm are compared to those achieved at 1030 nm. Retinal OCT at longer wavelengths, e.g. 1030 nm significantly improves the visualization of the retinal pigment epithelium/choriocapillaris/choroid interface and might therefore provide new insight into choroidal/choriocapillary changes in age-related macular degeneration and other diseases of the retinal pigment epithelium (RPE)-choroid complex. 1030 nm OCT could also become a valuable tool in monitoring treatment effects on the choroids as in Verteporfin therapy.
© (2005) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
A. Unterhuber, B. Povazay, B. Hermann, H. Sattmann, S. Michels, S. Sacu, C. Ahlers, C. Scholda, A. Chavez-Pirson, U. Schmidt-Erfurth, Adolf F. Fercher, and W. Drexler "In vivo retinal optical coherence tomography at 1030 nm with enhanced penetration into the choroid", Proc. SPIE 5861, Optical Coherence Tomography and Coherence Techniques II, 586103 (7 October 2005); https://doi.org/10.1117/12.632961
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