Economic burden analysis for UV radiation and vitamin D for colorectal cancer in the United States

Cedric F. Garland; Sharif B. Mohr; William B. Grant; Michael F. Holick

doi:10.1117/12.615158

18 August 2005 Economic burden analysis for UV radiation and vitamin D for colorectal cancer in the United States

Cedric F. Garland, Sharif B. Mohr, William B. Grant, Michael F. Holick

Proceedings Volume 5886, Ultraviolet Ground- and Space-based Measurements, Models, and Effects V; 58860P (2005) https://doi.org/10.1117/12.615158
Event: Optics and Photonics 2005, 2005, San Diego, California, United States

Abstract

Moderate exposure to sunlight is a key factor in maintaining adequate levels of vitamin D. Vitamin D sufficiency is associated with reduced incidence of many forms of cancer, osteoporotic fractures, multiple sclerosis, and other diseases. However, excessive ultraviolet radiation (UVR) exposure may be associated with melanoma and nonmelanoma skin cancer. An estimated 50,000-60,000 individuals die prematurely from cancer annually due to insufficient vitamin D in the US. The annual economic burden due to vitamin D insufficiency from inadequate exposure to solar ultraviolet B (UVB) or deficient oral intake is estimated at $46-65 billion, while that for excessive UVR exposure is $5-7 billion (1). Since excessive UVR exposure is not required for adequate vitamin D photosynthesis, increasing national guidelines for vitamin D intake and de-stigmatizing appropriate solar UVB exposure would substantially reduce medical care costs. This report describes an algorithm for estimating the annual number of dollars that could be saved and deaths from colorectal cancer that could be prevented by moderate daily exposure to sunlight or increased oral intake of vitamin D₃. If the assumptions of this analysis are valid, moderate exposure to sunlight or adequate oral intake of vitamin D₃ would prevent 10 deaths from colorectal cancer for every death from skin cancer that it might induce, and would save $11 billion per year. Reference: (1) Grant WB, Garland CF, Holick MF. Comparisons of estimated economic burdens due to insufficient solar ultraviolet (UV) irradiation or vitamin D and excess solar UV irradiation. Photochem Photobiol. In press.

Citation Download Citation

Cedric F. Garland, Sharif B. Mohr, William B. Grant, and Michael F. Holick "Economic burden analysis for UV radiation and vitamin D for colorectal cancer in the United States", Proc. SPIE 5886, Ultraviolet Ground- and Space-based Measurements, Models, and Effects V, 58860P (18 August 2005); https://doi.org/10.1117/12.615158

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KEYWORDS

Colorectal cancer

Skin cancer

Cancer

Melanoma

Ultraviolet radiation

Skin

Medicine

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