18 August 2005 Novel nanosystems enabling near IR multimodal imaging
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Abstract
Narrow and symmetric emission spectrum, continuous excitation spectrum, high quantum yields and resistance to photobleaching are outstanding advantages semiconductor nanoparticles exhibit ideally compared to conventional fluorescent dyes. However, it is still a challenge to replace existing organic fluorophores and develop a tool for imaging and site-specific drug delivery. In this presentation, we demonstrate the chemistry and spectroscopy of homogeneously alloyed nanocrystals and nanocrystal-doped protein microspheres, emitting the IR and near-infra red as tools for bio-imaging, and drug delivery, respectively. In addition, nanoparticles are studied as energy donors to photosensitizer phthalocyanine dyes, which have proven potential for photodynamic therapy.
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Smita Dayal, Robert Krolicki, Clemens Burda, "Novel nanosystems enabling near IR multimodal imaging", Proc. SPIE 5929, Physical Chemistry of Interfaces and Nanomaterials IV, 59290D (18 August 2005); doi: 10.1117/12.619137; https://doi.org/10.1117/12.619137
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