In this paper, an experimental study is conducted to investigate three light uniformers based on liquid guide for their possible usages as color mixing elements. In this study, three types of light uniformers are systematically analyzed, which include a straight light guide, a tapered light guide, and a U-shaped light guide. This study consists of two parts: a computer-aided optical modeling using a commercial ray tracing software package; and an experimental study verifying the results obtained from the computer simulations. Beam uniformity, in terms of illuminance and color, is compared among different light uniformers. The experimentally observed results agree well with the simulated results. Light transmission efficiency is also calculated for each light uniformer based on the simulation results. It is found in this study that the U-shaped light uniformer has high light transmission efficiency and the best color mixing effect among the three investigated light guides and offers a compact, practical, and inexpensive solution for color mixing in many industries.