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26 September 2005 Laser induced fluorescence system for detection of biological agents: European project FABIOLA
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Abstract
The Research and Technology Project FABIOLA (Fluorescence Applied to BIOLogical Agents Detection) is placed under the Common European Priority Area (CEPA) number 13 on "Radiological, chemical and biological defence" and managed by the Western European Armaments Organization (WEAO) in the frame of SOCRATE MOU (System of Co-operation for Research and Technology in Europe). The six (6) Nations: Finland, France, Greece, Italy, Poland and Sweden have decided to allocate funding to FABIOLA Research and Technology Project with France as the Lead Nation. There are two main objectives of the project : demonstrate the feasibility to improve the detection of BW agents using LIF (Laser Induced Fluorescence), and develop a BW early warning point detection lab-demonstrator based on LIF. The aim of the project is to evaluate the possibility of time-resolved fluorescence and conception of a system used for real-time measurements. It is well known that when bacteria are excited with UV radiation, they exhibit intense fluorescence emission. UV fluorescence is usually very good at discriminating bio from non-bio particle. Laser induced fluorescence is possible at several wavelength. For LIF system the laser source(s) should operate at excitation wavelength in the UV (250nm to 360nm) and the resulting fluorescence (300nm to 600nm) shall be detected with the aim to discriminate between bio-molecular materials (containing amino acids such as tryptophane, tyrosine, and phenylalanie, as well as cell nucleus compounds such as NADH and riboflavin).
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Krzysztof Kopczynski, Miroslaw Kwasny, Zygmunt Mierczyk, and Zbigniew Zawadzki "Laser induced fluorescence system for detection of biological agents: European project FABIOLA", Proc. SPIE 5954, Optical Security Systems, 595405 (26 September 2005); https://doi.org/10.1117/12.623013
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